Spiking networks that efficiently process dynamic sensory features explain receptor information mixing in somatosensory cortex

Koren V, Emanuel AJ, Panzeri S

bioRxiv, June 8, 2024

Nerve injury disrupts temporal processing in the spinal cord dorsal horn through alterations in PV+ interneurons

Rankin G, Chirila AM, Emanuel AJ, Zhang Z, Woolf CJ, Drugowitsch J, Ginty DD

Cell Reports, January 31, 2024


The multistable melanopsin of mammals

Emanuel AJ, Do MTH

Frontiers in Ophthalmology, April 26, 2023

Encoding of environmental illumination by primate melanopsin neurons
Liu A*, Milner ES*, Peng Y-R, Blume HA, Brown MC, Bryman GS, Emanuel AJ, Morquette P, Viet N-M, Sanes JR, Gamlin PD, Do MTH
Science, January 26, 2023
*equal contributions



Mechanoreceptor signal convergence and transformation in the dorsal horn flexibly shape a diversity of outputs to the brain

Chirila AM*, Rankin G*, Tseng S-Y, Emanuel AJ, Chavez-Martinez CL, Zhang D, Harvey CD, Ginty, DD

Cell, November 23, 2022

*equal contributions


Cortical responses to touch reflect subcortical integration of LTMR signals

Emanuel AJ, Lehnert BP, Panzeri P, Harvey CD, Ginty DD

Nature, December 23, 2021

Mechanoreceptor synapses in the brainstem shape the central representation of touch

Lehnert BP*, Santiago C*, Huey EL, Emanuel AJ, Renauld S, Africawala N, Alkislar I, Zheng Y, Bai L, Koutsioumpa C, Hong JT, Magee AR, Harvey CD, Ginty DD

Cell, October 11, 2021

*equal contributions


Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception

Neubarth NL*, Emanuel AJ*, Liu Y*, Springel MW, Handler A, Zhang Q, Lehnert BP, Guo C, Orefice LL, Abdelaziz A, DeLisle MM, Iskols M, Rhyins J, Kim SJ, Cattel SJ, Regehr W, Harvey CD, Drugowitsch J, Ginty DD

Science, June 19, 2020

*equal contributions


Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models

Orefice LL, Mosko JR, Morency DT, Wells MF, Tasnim A, Mozeika SM, Ye M, Chirila AM, Emanuel AJ, Rankin G, Fame RM, Lehtinen MK, Feng G, Ginty DD

Cell, August 8, 2019


Biophysical Variation within the M1 Type of Ganglion Cell Photoreceptor

Emanuel AJ, Kapur K, Do MTH

Cell Reports, October 24, 2017


Melanopsin tristability for sustained and broadband phototransduction

Emanuel AJ, Do MTH

Neuron, March 4, 2015


Hindbrain Catecholamine Neurons Modulate the Growth Hormone But Not the Feeding Response to Ghrelin

Emanuel AJ, Ritter S

Endocrinology, July 7, 2010

The Lipoprivic Control of Feeding Is Governed by Fat Metabolism, Not by Leptin or Adipose Depletion

Hudson BD, Emanuel AJ, Wiater MF, Ritter S

Endocrinology, May 1, 2010

Cover Image: ChR2-EYFP expressed in layer IV pyramidal neurons.